Gallbladder cancer

Gallbladder cancer is an abnormal growth of cells that begins in the gallbladder.The gallbladder is a small, pear-shaped organ under the liver. Both the liver and the gallbladder are behind the right lower ribs. 

Gallbladder cancer signs and symptoms may include:

  • Abdominal pain, particularly in the upper right portion of the abdomen
  • Abdominal bloating
  • Losing weight without trying
  • Yellowing of the skin and whites of the eyes (jaundice

Some tests that may prove helpful in diagnosing gallbladder cancer include the following:

  • Liver function tests
  • CA 19-9 assay
  • Carcinoembryonic antigen (CEA) assay
  • Imaging studies

Ultrasonography (US) is a standard initial study in patients with right upper quadrant pain. A mass can be identified in 50-75% of patients with gallbladder cancer.

Computed tomography (CT) scans also may be useful in patients with upper abdominal pain and can demonstrate tumor invasion outside of the gallbladder and identify metastatic disease elsewhere in the abdomen or pelvis.

Percutaneous transhepatic cholangiography (PTC) or endoscopic retrograde cholangiography (ERCP) may establish the diagnosis of gallbladder cancer by bile cytology. Magnetic resonance cholangiopancreatography (MRCP) is a noninvasive way to take images of the bile ducts using the same type of machine used for standard MRI scans.

The main types of treatments used for gallbladder cancer include the following:

  • Surgery
  • Radiation therapy
  • Chemotherapy
  • Palliative therapy

Although complete surgical resection is the only therapy to afford a chance of cure, en bloc resections of the gallbladder and portal lymph nodes carry a high morbidity and mortality (similar to bile duct carcinoma). Nodal metastases outside of the regional area (ie, porta hepatis, gastrohepatic ligament, retroduodenal area) are not resectable.

Every examination and operation related to the disease should be performed by a properly equipped hospital with the latest medical technology and professional academic medical staff. The Turkish Health Group will definitely direct you to the hospitals with the most modern medical equipment and professional medical staff related to your disease. Contact us for more information and a free second medical reference from a professional Turkish doctors.